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GNE-3511 Catalog No : 1781006

Chemical Information

Product NameGNE-3511
Iupac Chemical Name2-((6-(3,3-difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile 
SynonymsGNE-3511;GNE 3511;GNE3511. 
Molecular FormulaC23H26F2N6O 
Molecular Weight440.5 
SmileFC1(CN(CC1)C1=CC(=CC(=N1)NC=1C=C(C#N)C=CN1)C1CCN(CC1)C1COC1)F
InChiKeyRHFIAUKMKYHHFA-UHFFFAOYSA-N
InChiInChI=1S/C23H26F2N6O/c24-23(25)4-8-31(15-23)22-11-18(17-2-6-30(7-3-17)19-13-32-14-19)10-21(29-22)28-20-9-16(12-26)1-5-27-20/h1,5,9-11,17,19H,2-4,6-8,13-15H2,(H,27,28,29)
Cas1496581-76-0

Technical Data

Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

GNE-3511 is a potent and selective dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models. 

Chemical Structure

1781006 - GNE-3511 | CAS 1496581-76-0

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