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740 Y-P (PDGFR 740Y-P) Catalog No : 17021302

Chemical Information

Product Name740 Y-P (PDGFR 740Y-P)
Iupac Chemical Name740 Y-P (PDGFR 740Y-P) 
SynonymsN/A 
Molecular FormulaC141H222N43O39PS3 
Molecular Weight3270.70 
InChiKey
InChi
Cas1236188-16-1

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

740 Y-P is cell-permeable phosphopeptide activator of PI3K.

The PDGFR 740Y-P peptide stimulates a mitogenic response in muscle cells. The ability of the 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell permeable SH2 domain binding peptides. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose dependent and does not require insulin.

 

Chemical Structure

17021302 - 740 Y-P (PDGFR 740Y-P) | CAS 1236188-16-1

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