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AG 879 Catalog No : 1811303

Chemical Information

Product NameAG 879
Iupac Chemical Name2-Propenethioamide, 3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-2-cyano-, (E)-
SynonymsAG 879; AG879; AG-879; Tyrphostin AG 879;
Molecular FormulaC18H24N2OS
Molecular Weight316.46
SmileS=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
InChiKeyXRZYELWZLNAXGE-KPKJPENVSA-N
InChiInChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)/b12-7+
Cas148741-30-4

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

AG-879 is a tyrphostin compound that inhibits nerve growth factor-dependent TrkA tyrosine phosphorylation in PC-12 cells, HER2-ErbB2 kinase in several breast and ovarian cancer cell lines, and the VEGF receptor FLK1.

Chemical Structure

1811303 - AG 879 | CAS 148741-30-4

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