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AST487 Catalog No : 186158

Chemical Information

Product NameAST487
Iupac Chemical Name1-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea
SynonymsNVPAST487; AST 487; AST487; AST-487.
Molecular FormulaC26H30F3N7O2
Molecular Weight529.56
SmileO=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3
InChiKeyODPGGGTTYSGTGO-UHFFFAOYSA-N
InChiInChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)
Cas630124-46-8

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

AST487, also known as NVP- AST487, is a RET kinase inhibitor/FLT3 inhibitor.

Chemical Structure

186158 - AST487 | CAS 630124-46-8

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