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AX-024 HCl Catalog No : 181254

Chemical Information

Product NameAX-024 HCl
Iupac Chemical Name1-((4-(4-Fluorophenyl)-6-methoxy-2H-chromen-3-yl)methyl)pyrrolidine hydrochloride
SynonymsAX-024; AX 024; AX024 HCl; AX-024 hydrochloride.
Molecular FormulaC21H23ClFNO2
Molecular Weight375.8684
SmileCOC1=CC(C(C2=CC=C(F)C=C2)=C(CN3CCCC3)CO4)=C4C=C1.[H]Cl
InChiKeyDGBCIMPGYRVTPD-UHFFFAOYSA-N
InChiInChI=1S/C21H22FNO2.ClH/c1-24-18-8-9-20-19(12-18)21(15-4-6-17(22)7-5-15)16(14-25-20)13-23-10-2-3-11-23;/h4-9,12H,2-3,10-11,13-14H2,1H3;1H
Cas1704801-24-0

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM).

Chemical Structure

181254 - AX-024 HCl  | CAS 1704801-24-0

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