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Arctiin Catalog No : 17021323

Chemical Information

Product NameArctiin
Iupac Chemical NameArctiin 
SynonymsArctigenin-4-Glucoside, NSC 315527 
Molecular FormulaC27H34O11 
Molecular Weight534.55 
SmileCOc1ccc(cc1OC)C[[email protected]]2COC(=O)[[email protected]@H]2Cc3ccc(c(c3)OC)O[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O4)CO)O)O)O
InChiKeyXOJVHLIYNSOZOO-SWOBOCGESA-N
InChiInChI=1S/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1
Cas20362-31-6
MDLMFCD00870630

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

Arctiin acts on an agonists of the adiponectin receptor 1 with anti-cancer effects.

Arctiin induces growth inhibition and dephosphorylates the tumor-suppressor retinoblastoma protein in human immortalized keratinocyte HaCaT cells. The growth inhibition caused by arctiin is associated with the downregulation of cyclin D1 protein expression. The arctiin-induced suppression of cyclin D1 protein expression occurs in various types of human tumor cells, including osteosarcoma, lung, colorectal, cervical and breast cancer, melanoma, transformed renal cells and prostate cancer.

 

Chemical Structure

17021323 - Arctiin | CAS 20362-31-6

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