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BBT-594 Catalog No : 179133

Chemical Information

Product NameBBT-594
Iupac Chemical Name5-((6-acetamidopyrimidin-4-yl)oxy)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)indoline-1-carboxamide
SynonymsBBT-594; BBT-594; BBT-594; NVP-BBT594; NVP BBT594; NVP BBT-594.
Molecular FormulaC28H30F3N7O3
Molecular Weight569.59
SmileC(C)(=O)NC1=CC(=NC=N1)OC=1C=C2CCN(C2=CC1)C(=O)NC1=CC(=C(C=C1)CN1CCN(CC1)C)C(F)(F)F
InChiKeyVQLNKQZLPGLOSI-UHFFFAOYSA-N
InChiInChI=1S/C28H30F3N7O3/c1-18(39)34-25-15-26(33-17-32-25)41-22-5-6-24-19(13-22)7-8-38(24)27(40)35-21-4-3-20(23(14-21)28(29,30)31)16-37-11-9-36(2)10-12-37/h3-6,13-15,17H,7-12,16H2,1-2H3,(H,35,40)(H,32,33,34,39)
Cas882405-89-2

Technical Data

Appearanceoff-white solid
Purity98.0%
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
Quality control

Description

BBT594, also known as NVP-BBT594, is potent and selective RET and JAK2 inhibitor. NVP-BBT594 impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells.

Chemical Structure

179133 - BBT-594 | CAS 882405-89-2

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