Login +0086-27-65522453 [email protected]

BIIB021 Catalog No : 16122868

Chemical Information

Product NameBIIB021
Iupac Chemical NameBIIB021 
SynonymsBIIB 021; BIIB-021; CNF-2024; CNF 2024; CNF2024 
Molecular FormulaC14H15ClN6O 
Molecular Weight318.76 
SmileCc1cnc(c(c1OC)C)Cn2cnc3c2nc(nc3Cl)N
InChiKeyQULDDKSCVCJTPV-UHFFFAOYSA-N
InChiInChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20)
Cas848695-25-0
MDLMFCD15528939

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations. 

Chemical Structure

16122868 - BIIB021 | CAS 848695-25-0

Package

SizePrice
Login to get price

Quick Order

Change

Contact Us