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BMS-777607 Catalog No : 121417

Chemical Information

Product NameBMS-777607
Iupac Chemical NameN-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide 
SynonymsBMS777607; BMS 777607 
Molecular FormulaC25H19ClF2N4O4 
Molecular Weight512.893 
SmileCCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
InChiKeyVNBRGSXVFBYQNN-UHFFFAOYSA-N
InChiInChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
Cas1025720-94-8; 1196681-44-3

Technical Data

AppearanceOff-white Solid powder to light-yellow solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

BMS-777607 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway. 

Chemical Structure

121417 - BMS-777607 | CAS 1025720-94-8; 1196681-44-3

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