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BMS-794833 Catalog No : 52205

Chemical Information

Product NameBMS-794833
Iupac Chemical NameN-(4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamide 
SynonymsN/A 
Molecular FormulaC23H15ClF2N4O3 
Molecular Weight468.84 
SmileNC1=NC=CC(=C1Cl)OC1=C(C=C(C=C1)NC(=O)C1=CNC=C(C1=O)C1=CC=C(C=C1)F)F
InChiKeyPDYXPCKITKHFOZ-UHFFFAOYSA-N
InChiInChI=1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H,(H2,27,29)(H,28,31)(H,30,32)
Cas1174046-72-0

Technical Data

Appearancesolid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 
Quality control

Description

BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7/15 nM; also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. 

Chemical Structure

52205 - BMS-794833 | CAS 1174046-72-0

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