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BMS-911543 Catalog No : 010817

Chemical Information

Product NameBMS-911543
Iupac Chemical NameN,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo(4,5-d)pyrrolo(2,3b)pyridine-7-carboxamide 
SynonymsBMS911543; BMS 911543 
Molecular FormulaC23H28N8O 
Molecular Weight432.521 
SmileCCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6
InChiKeyJCINBYQJBYJGDM-UHFFFAOYSA-N
InChiInChI=1S/C23H28N8O/c1-5-30-17(23(32)31(14-6-7-14)15-8-9-15)11-16-20-19(24-12-28(20)3)21(26-22(16)30)25-18-10-13(2)29(4)27-18/h10-12,14-15H,5-9H2,1-4H3,(H,25,26,27)
Cas1271022-90-2

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

BMS-911543 is a potent and selective small-molecule inhibitor of JAK2; displayes potent anti-proliferative and pharmacodynamic effects in cell lines dependent upon JAK2 signaling.
 

Chemical Structure

010817 - BMS-911543 | CAS 1271022-90-2

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