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CHIR98014 Catalog No : 110601

Chemical Information

Product NameCHIR98014
Iupac Chemical Name6-N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine 
SynonymsCHIR-98014; CHIR 98014 
Molecular FormulaC20H17Cl2N9O2 
Molecular Weight486.31 
SmileC1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2C3=NC=CN3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N
InChiKeyNDFXSHIIGXVOKT-UHFFFAOYSA-N
InChiInChI=1S/C20H17Cl2N9O2/c21-11-1-2-12(14(22)9-11)17-13(19-25-6-7-26-19)10-28-20(30-17)27-8-5-24-16-4-3-15(31(32)33)18(23)29-16/h1-4,6-7,9-10H,5,8H2,(H,25,26)(H3,23,24,29)(H,27,28,30)
Cas556813-39-9

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

CHIR98014 is a reversible, cell-permeable inhibitor of GSK3 and GSK3. It is inactive against a series of other serine/threonine or tyrosine kinases. 

Chemical Structure

110601 - CHIR98014 | CAS 556813-39-9

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