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DCC-2618 Catalog No : 1811121

Chemical Information

Product NameDCC-2618
Iupac Chemical Name1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea
SynonymsDCC-2618; DCC 2618; DCC2618; Ripretinib;
Molecular FormulaC24H21BrFN5O2
Molecular Weight510.3674
SmileO=C(NC1=CC(C2=CC3=C(C=C(NC)N=C3)N(CC)C2=O)=C(Br)C=C1F)NC4=CC=CC=C4
InChiKeyCEFJVGZHQAGLHS-UHFFFAOYSA-N
InChiInChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33)
Cas1442472-39-0

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Ripretinib, also known as DCC-2618, is a potent, orally active and selective KIT/PDGFR inhibitor with potential antineoplastic activity.

Chemical Structure

1811121 - DCC-2618 | CAS 1442472-39-0

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