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Derazantinib Catalog No : 189273

Chemical Information

Product NameDerazantinib
Iupac Chemical Name(6R)-6-(2-fluorophenyl)-N-(3-{2-[(2-methoxyethyl)amino]ethyl}phenyl)-5,6-dihydrobenzo[h]quinazolin-2-amine
SynonymsARQ 087; ARQ087; AR-Q087; Derazantinib
Molecular FormulaC29H29FN4O
Molecular Weight468.5764
SmileCOCCNCCC1=CC(NC2=NC=C3C[[email protected]@H](C4=CC=CC=C4F)C5=CC=CC=C5C3=N2)=CC=C1
InChiKeyKPJDVVCDVBFRMU-AREMUKBSSA-N
InChiInChI=1S/C29H29FN4O/c1-35-16-15-31-14-13-20-7-6-8-22(17-20)33-29-32-19-21-18-26(24-10-4-5-12-27(24)30)23-9-2-3-11-25(23)28(21)34-29/h2-12,17,19,26,31H,13-16,18H2,1H3,(H,32,33,34)/t26-/m1/s1
Cas1234356-69-4

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Derazantinib, also known as ARQ-087, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity.

Chemical Structure

189273 - Derazantinib  | CAS 1234356-69-4

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