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Dovitinib lactate Catalog No : 18575

Chemical Information

Product NameDovitinib lactate
Iupac Chemical Name4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-hydroxypropanoate
SynonymsTKI258; TKI-258; TKI 258; CHIR258; CHIR-258; CHIR 258; Dovitinib lactate
Molecular FormulaC24H27FN6O4
Molecular Weight482.51
SmileO=C1NC2=C(C(F)=CC=C2)C(N)=C1C3=NC4=CC=C(N5CCN(C)CC5)C=C4N3.CC(O)C(O)=O
InChiKeyZRHDKBOBHHFLBW-UHFFFAOYSA-N
InChiInChI=1S/C21H21FN6O.C3H6O3/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29;1-2(4)3(5)6/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29);2,4H,1H3,(H,5,6)
Cas915769-50-5

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Dovitinib, also known as TKI-258 or CHIR-258, is an orally bioavailable FGFR3 inhibitor.

Chemical Structure

18575 - Dovitinib lactate | CAS 915769-50-5

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