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GDC-0575 Catalog No : 189272

Chemical Information

Product NameGDC-0575
Iupac Chemical Name(R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide
SynonymsGDC0575 (ARRY-575,RG7441);Cyclopropanecarboxamide, N-[4-[(3R)-3-amino-1-piperidinyl]-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl]-;EOS-61380;ARRY-575;ARRY-575, RG7741;GDC-0575 (ARRY-575, RG7741)
Molecular FormulaC16H20BrN5O
Molecular Weight378.27
InChiKey
InChi
Cas1196541-47-5

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature as non-hazardous chemical.
Quality control

Description

GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of 1.2 nM.

Chemical Structure

189272 - GDC-0575  | CAS 1196541-47-5

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