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GDC-0927 Catalog No : 1811301

Chemical Information

Product NameGDC-0927
Iupac Chemical Name(2S)-2-(4-{2-[3-(Fluoromethyl)-1-azetidinyl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol
SynonymsGDC-0927; GDC 0927; GDC0927; SRN-927; SRN 927; SRN927.
Molecular FormulaC28H28FNO4
Molecular Weight461.53
SmileOC1=CC(C(C)=C(C2=CC=CC(O)=C2)[[email protected]](C3=CC=C(OCCN4CC(CF)C4)C=C3)O5)=C5C=C1
InChiKeyKJAAPZIFCQQQKX-NDEPHWFRSA-N
InChiInChI=1S/C28H28FNO4/c1-18-25-14-23(32)7-10-26(25)34-28(27(18)21-3-2-4-22(31)13-21)20-5-8-24(9-6-20)33-12-11-30-16-19(15-29)17-30/h2-10,13-14,19,28,31-32H,11-12,15-17H2,1H3/t28-/m0/s1
Cas1642297-01-5

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

GDC-0927, also known as SRN-927, is a next-generation oral SERD which appears to have greater potential than GDC-0810 to be a best-in-class SERD molecule.

Chemical Structure

1811301 - GDC-0927 | CAS 1642297-01-5

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