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GLPG1837 Catalog No : 1842811

Chemical Information

Product NameGLPG1837
Iupac Chemical NameN-(3-carbamoyl-5,5,7,7-tetramethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide
SynonymsGLPG-1837; GLPG 1837; GLPG1837; ABBV-974; ABBV 974; ABBV974.
Molecular FormulaC16H20N4O3S
Molecular Weight348.421
SmileO=C(C1=NNC=C1)NC(S2)=C(C(N)=O)C3=C2C(C)(C)OC(C)(C)C3
InChiKeyGHTGYZMBQPXTCQ-UHFFFAOYSA-N
InChiInChI=1S/C16H20N4O3S/c1-15(2)7-8-10(12(17)21)14(24-11(8)16(3,4)23-15)19-13(22)9-5-6-18-20-9/h5-6H,7H2,1-4H3,(H2,17,21)(H,18,20)(H,19,22)
Cas1654725-02-6

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

GLPG-1837, also known as ABBV-974, is a novel cystic fibrosis transmembrane conductance regulator (CFTR) potentiator1.

Chemical Structure

1842811 - GLPG1837 | CAS 1654725-02-6

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