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GNF-2 Catalog No : 52301

Chemical Information

Product NameGNF-2
Iupac Chemical Name3-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide 
Molecular FormulaC18H13F3N4O2 
Molecular Weight374.32 
SmileO=C(N)C1=CC=CC(C2=NC=NC(NC3=CC=C(OC(F)(F)F)C=C3)=C2)=C1
InChiKeyWEVYNIUIFUYDGI-UHFFFAOYSA-N
InChiInChI=1S/C18H13F3N4O2/c19-18(20,21)27-14-6-4-13(5-7-14)25-16-9-15(23-10-24-16)11-2-1-3-12(8-11)17(22)26/h1-10H,(H2,22,26)(H,23,24,25)
Cas778270-11-4

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activity (IC50 = 0.14 M). 

Chemical Structure

52301 - GNF-2 | CAS 778270-11-4

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