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GSK269962A Catalog No : 102206

Chemical Information

Product NameGSK269962A
Iupac Chemical NameN-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c] pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide 
SynonymsGSK 269962A; GSK-269962A; GSK269962; GSK 269962; GSK-269962 
Molecular FormulaC29H30N8O5 
Molecular Weight570.6 
SmileNC=1C(=NON1)C=1N(C2=C(C=NC(=C2)OC=2C=C(C=CC2)NC(C2=CC=C(C=C2)OCCN2CCOCC2)=O)N1)CC
InChiKeyYOVNFNXUCOWYSG-UHFFFAOYSA-N
InChiInChI=1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/h3-9,16-18H,2,10-15H2,1H3,(H2,30,35)(H,32,38)
Cas850664-21-0

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

GSK269962A(CAS 850664-21-0) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively); displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. 

Chemical Structure

102206 - GSK269962A | CAS 850664-21-0

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