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GSK2982772 Catalog No : 178911

Chemical Information

Product NameGSK2982772
Iupac Chemical Name1H-​1,​2,​4-​Triazole-​5-​carboxamide, 3-​(phenylmethyl)​-​N-​[(3S)​-​2,​3,​4,​5-​tetrahydro-​5-​methyl-​4-​oxo-​1,​5-​benzoxazepin-​3-​yl]​- 
SynonymsN/A 
Molecular FormulaC20H19N5O3 
Molecular Weight377.40 
SmileC1(=CC=CC=C1)CC1=NNC(=N1)C(=O)N[[email protected]]1COC2=C(N(C1=O)C)C=CC=C2
InChiKeyLYPAFUINURXJSG-AWEZNQCLSA-N
InChiInChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(23-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24)/t14-/m0/s1
Cas1622848-92-3

Technical Data

Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

GSK2982772 is an ATP competitive eceptor-interacting protein-1 (RIP1) kinase inhibitor with the IC50 value of 1 nM. It has exquisite kinase specificity and excellent activity in blocking many TNF-dependent cellular responses. 

Chemical Structure

178911 - GSK2982772 | CAS 1622848-92-3

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