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GSK429286A Catalog No : 52629

Chemical Information

Product NameGSK429286A
Molecular FormulaC21H16F4N4O2 
Molecular Weight432.37 
SmileCC1=C(C(CC(=O)N1)c2ccc(cc2)C(F)(F)F)C(=O)Nc3cc4cn[nH]c4cc3F
InChiKeyOLIIUAHHAZEXEX-UHFFFAOYSA-N
InChiInChI=1S/C21H16F4N4O2/c1-10-19(20(31)28-17-6-12-9-26-29-16(12)8-15(17)22)14(7-18(30)27-10)11-2-4-13(5-3-11)21(23,24)25/h2-6,8-9,14H,7H2,1H3,(H,26,29)(H,27,30)(H,28,31)
Cas864082-47-3
MDLMFCD16618404

Technical Data

SolubilityDMSO 51 mg/ml 
Quality control

Description

GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM, respectively. 

Chemical Structure

52629 - GSK429286A | CAS 864082-47-3

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