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GSK503 Catalog No : 51805

Chemical Information

Product NameGSK503
Iupac Chemical NameN-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide 
SynonymsGSK-503 
Molecular FormulaC31H38N6O2 
Molecular Weight526.67 
SmileO=C(C1=CC(C2=CC=C(N3CCN(C)CC3)N=C2)=CC4=C1C(C)=CN4C(C)C)NCC5=C(C)C=C(C)NC5=O
InChiKeyHRDQQHUKUIKFHT-UHFFFAOYSA-N
InChiInChI=1S/C31H38N6O2/c1-19(2)37-18-21(4)29-25(30(38)33-17-26-20(3)13-22(5)34-31(26)39)14-24(15-27(29)37)23-7-8-28(32-16-23)36-11-9-35(6)10-12-36/h7-8,13-16,18-19H,9-12,17H2,1-6H3,(H,33,38)(H,34,39)
Cas1346572-63-1

Technical Data

Appearancecrystalline solid 
Purity98% 
Solubility10 mM in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

GSK-503 is a potent EZH2 inhibitor with potential anticancer activity.

Reference:
1. Cancer Cell. 2013 May 13; 23(5): 677C692.

 

Chemical Structure

51805 - GSK503 | CAS 1346572-63-1

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