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GSK872 Catalog No : 17101621

Chemical Information

Product NameGSK872
SynonymsGSK872; GSK-872; GSK 872;
Molecular FormulaC19H17N3O2S2
Molecular Weight383.484
SmileO=S(C1=CC=C2N=CC=C(NC3=CC=C(SC=N4)C4=C3)C2=C1)(C(C)C)=O
InChiKeyZCDBTQNFAPKACC-UHFFFAOYSA-N
InChiInChI=1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22)
Cas1346546-69-7

Technical Data

Appearanceoff-white solid
Purity>98%
SolubilitySoluble in DMSO, not in water
Storage3 years -20ºCpowder
Shipping ConditionShipped under ambient temperature
Quality control

Description

GSK872 is a a receptor interacting protein kinase-3 (RIP3) inhibitor. GSK872 inhibits TNF- and virus-induced necrosis in 3T3-SA fibroblasts. It also inhibits necrosis induced by toll-like receptor 3 (TLR3).

Chemical Structure

17101621 - GSK872 | CAS 1346546-69-7

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