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GW788388 Catalog No : 52305

Chemical Information

Product NameGW788388
Iupac Chemical Name4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide 
SynonymsGW788388;GW-788388 
Molecular FormulaC25H23N5O2 
Molecular Weight425.48 
SmileO=C(NC1CCOCC1)C2=CC=C(C3=NC=CC(C4=CNN=C4C5=NC=CC=C5)=C3)C=C2
InChiKeySAGZIBJAQGBRQA-UHFFFAOYSA-N
InChiInChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31)
Cas452342-67-5

Technical Data

Appearancecrystalline solid 
Purity98% 
Solubility2mg/ml in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibits TGF- type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor. 

Chemical Structure

52305 - GW788388 | CAS 452342-67-5

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