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Galunisertib(LY2157299) Catalog No : 52017

Chemical Information

Product NameGalunisertib(LY2157299)
Iupac Chemical Name4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide 
SynonymsGalunisertib,LY2157299,LY-2157299,LY 2157299 
Molecular FormulaC22H19N5O 
Molecular Weight369.42 
SmileCC1=CC=CC(=N1)C=1C(=C2N(N1)CCC2)C2=CC=NC1=CC=C(C=C21)C(=O)N
InChiKeyIVRXNBXKWIJUQB-UHFFFAOYSA-N
InChiInChI=1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
Cas700874-72-2

Technical Data

Appearanceoff-white solid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Galunisertib (LY2157299) is selective TGF- receptor kinase inhibitor. Galunisertib was found to inhibit the growth in an in vitro clonogenic assay in 6.3% (5/79) of the examined PDX.
 

Chemical Structure

52017 - Galunisertib(LY2157299) | CAS 700874-72-2

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