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Genz-123346 Catalog No : S1419

Chemical Information

Product NameGenz-123346
Iupac Chemical NameN-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)nonanamide 
SynonymsGenz-123346;Genz123346;Genz 123346 
Molecular FormulaC24H38N2O4 
Molecular Weight418.57 
SmileO1C2=C(OCC1)C=C(C=C2)[[email protected]]([[email protected]@H](CN2CCCC2)NC(CCCCCCCC)=O)O
InChiKeyJMNXWOFCUJJYEO-HYBUGGRVSA-N
InChiInChI=1S/C24H38N2O4/c1-2-3-4-5-6-7-10-23(27)25-20(18-26-13-8-9-14-26)24(28)19-11-12-21-22(17-19)30-16-15-29-21/h11-12,17,20,24,28H,2-10,13-16,18H2,1H3,(H,25,27)/t20-,24-/m1/s1
Cas491833-30-8

Technical Data

Appearanceoff-white solid 
Purity98% 
Solubility50mg/ml in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature. 
Quality control

Description

Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM 

Chemical Structure

S1419 - Genz-123346 | CAS 491833-30-8

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