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Neflamapimod Catalog No : 1791317

Chemical Information

Product NameNeflamapimod
Iupac Chemical Name5-(2,6-Dichlorophenyl)-2-(2,4-difluorophenylsulfanyl)-6H-pyrimido[3,4-b]pyridazin-6-one
SynonymsVX-745; VX 745; VX745; VRT-031745, VD-31745; Neflamapimod.
Molecular FormulaC19H9Cl2F2N3OS
Molecular Weight436.26
SmileClC1=C(C(=CC=C1)Cl)C=1C(N=CN2N=C(C=CC21)SC2=C(C=C(C=C2)F)F)=O
InChiKeyVEPKQEUBKLEPRA-UHFFFAOYSA-N
InChiInChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H
Cas209410-46-8

Technical Data

Appearanceoff-white solid
Purity98.0%
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
Quality control

Description

Neflamapimod, also known as VX-745, VRT-031745 and VD-31745, is highly potent and selective p38α inhibitor (IC50 = 10 nM).

Chemical Structure

1791317 - Neflamapimod | CAS 209410-46-8

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