Login +0086-27-65522453 [email protected]

ODM-201(BAY-1841788) Catalog No : 123101

Chemical Information

Product NameODM-201(BAY-1841788)
Iupac Chemical NameN-((R)-1-(3-(4-cyano-3-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 
SynonymsBAY-1841788;ODM-201;ODM201;ODM 201;BAY1841788;BAY 1841788 
Molecular FormulaC19H19ClN6O2 
Molecular Weight398.85 
SmileO=C(C1=NNC(C(O)C)=C1)N[[email protected]](C)CN2N=C(C3=CC=C(C#N)C(C(F)(F)F)=C3)C=C2

Technical Data

AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control


ODM-201(also known as BAY-1841788)is a novel, nonsteroidal, orally active AR inhibitor that inhibits potently androgen binding to AR and androgen-induced nuclear translocation of AR in AR overexpressing cells.
ODM-201 has been studied in phase I and phase II clinical trials and has thus far been found to be effective and well-tolerated, with the most commonly reported side effects including fatigue, nausea,and diarrhea. No seizures have been observed. As of July 2015, ODM-201 is in phase III trials for CRPC.

ORM-15341 is the main active metabolite of ODM-201. It, similarly, is a full antagonist of the AR, with an affinity (Ki) of 8 nM and an IC50 of 38 nM.


Chemical Structure

123101 - ODM-201(BAY-1841788) | CAS 1297538-32-9


Login to get price

Quick Order


Contact Us