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OSI-420(Desmethyl Erlotinib) Catalog No : 166215

Chemical Information

Product NameOSI-420(Desmethyl Erlotinib)
Iupac Chemical NameEthanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]- 
SynonymsROSCOVITINE(CVC202);CP373420;OSI420;C-P373420;Desmethyl Erlotinib 
Molecular FormulaC21H21N3O4 
Molecular Weight379.41 
SmileCOCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCO
InChiKeyKOQIAZNBAWFSQM-UHFFFAOYSA-N
InChiInChI=1S/C21H21N3O4/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21/h1,4-6,11-14,25H,7-10H2,2H3,(H,22,23,24)
Cas183321-86-0

Technical Data

AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

OSI-420 is the active metabolite of Erlotinib which is an orally active EGFR tyrosin kinase inhibitor. 

Chemical Structure

166215 - OSI-420(Desmethyl Erlotinib) | CAS 183321-86-0

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