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OTX015 Catalog No : 111012

Chemical Information

Product NameOTX015
Iupac Chemical Name(S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide 
SynonymsOTX 015; OTX015 
Molecular FormulaC25H22ClN5O2S 
Molecular Weight491.992 
SmileO=C(NC1=CC=C(O)C=C1)C[[email protected]]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2
InChiKeyGNMUEVRJHCWKTO-FQEVSTJZSA-N
InChiInChI=1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33)/t20-/m0/s1
Cas202590-98-5

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

OTX-015 is a new potent BRD2/3/4 inhibitor with evident anti-proliferative activity in several cell lines representative of mature B-cell tumors. 

Chemical Structure

111012 - OTX015 | CAS 202590-98-5

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