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QNZ46 Catalog No : 91006

Chemical Information

Product NameQNZ46
Iupac Chemical Name4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid 
SynonymsQNZ-46 
Molecular FormulaC24H17N3O6 
Molecular Weight443.408 
SmileCOC=1C=C2C(N(C(=NC2=CC1)\C=C\C1=CC(=CC=C1)[N+](=O)[O-])C1=CC=C(C(=O)O)C=C1)=O
InChiKeyGNLVJIICVWDSNI-LFYBBSHMSA-N
InChiInChI=1S/C24H17N3O6/c1-33-19-10-11-21-20(14-19)23(28)26(17-8-6-16(7-9-17)24(29)30)22(25-21)12-5-15-3-2-4-18(13-15)27(31)32/h2-14H,1H3,(H,29,30)/b12-5+
Cas1237744-13-6

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

QNZ46 is a noncompetitive and voltage-independent antagonist selective for NR2C/D containing NMDA receptors (IC50 = 6, 3, 229, and >300 M for NR2C, NR2D, NR2A, and NR2B, respectively). Inhibition on NR2C/D containing NMDA receptors is glutamate-binding, but not glycine-binding, dependent.
 

Chemical Structure

91006 - QNZ46 | CAS 1237744-13-6

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