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Ribociclib (LEE011) Catalog No : 51911

Chemical Information

Product NameRibociclib (LEE011)
Iupac Chemical Name7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide 
SynonymsRibociclib;LEE011 
Molecular FormulaC23H30N8O 
Molecular Weight434.54 
SmileC1(CCCC1)N1C(=CC2=C1N=C(N=C2)NC2=NC=C(C=C2)N2CCNCC2)C(=O)N(C)C
InChiKeyRHXHGRAEPCAFML-UHFFFAOYSA-N
InChiInChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)
Cas1211441-98-3

Technical Data

Appearanceyellow solid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor. Phase 3 

Chemical Structure

51911 - Ribociclib (LEE011) | CAS 1211441-98-3

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