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Rilpivirine HCl Catalog No : 17011601

Chemical Information

Product NameRilpivirine HCl
Iupac Chemical Name(E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile hydrochloride 
SynonymsRilpivirine hydrochloride; TMC278; TMC-278; TMC 278. trade name Edurant 
Molecular FormulaC22H19ClN6 
Molecular Weight402.886 
SmileCl.C(#N)/C=C/C1=CC(=C(C(=C1)C)NC1=NC(=NC=C1)NC1=CC=C(C#N)C=C1)C
InChiKeyKZVVGZKAVZUACK-BJILWQEISA-N
InChiInChI=1S/C22H18N6.ClH/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19;/h3-9,11-13H,1-2H3,(H2,25,26,27,28);1H/b4-3+;
Cas700361-47-3

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

Rilpivirine, also known as TMC278, is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. Rilpivirine was approved for use in the United States in May 2011. 

Chemical Structure

17011601 - Rilpivirine HCl | CAS 700361-47-3

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