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Rogaratinib Catalog No : 192277

Chemical Information

Product NameRogaratinib
Iupac Chemical Name4-((4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)methyl)piperazin-2-one
SynonymsRogaratinib; BAY-1163877: BAY1163877: BAY 1163877
Molecular FormulaC23H26N6O3S
Molecular Weight466.56
SmileO=C1NCCN(CC2=C(COC)C(C3=CC4=CC(C)=CC(OC)=C4S3)=C5C(N)=NC=NN52)C1
InChiKeyHNLRRJSKGXOYNO-UHFFFAOYSA-N
InChiInChI=1S/C23H26N6O3S/c1-13-6-14-8-18(33-22(14)17(7-13)32-3)20-15(11-31-2)16(9-28-5-4-25-19(30)10-28)29-21(20)23(24)26-12-27-29/h6-8,12H,4-5,9-11H2,1-3H3,(H,25,30)(H2,24,26,27)
Cas1443530-05-9

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor receptor (FGFR) inhibitor.

Chemical Structure

192277 - Rogaratinib | CAS 1443530-05-9

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