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Tideglusib Catalog No : 161009028

Chemical Information

Product NameTideglusib
Iupac Chemical Name2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione 
SynonymsNP031112; NP 031112; NP-031112; Tideglusib. 
Molecular FormulaC19H14N2O2S 
Molecular Weight334.393 
SmileC1(=CC=CC2=CC=CC=C12)N1SC(N(C1=O)CC1=CC=CC=C1)=O
InChiKeyPMJIHLSCWIDGMD-UHFFFAOYSA-N
InChiInChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2
Cas865854-05-3

Technical Data

AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Tideglusib protects neural stem cells against NMDA receptor overactivation. Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial. Tideglusib prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders.  

Chemical Structure

161009028 - Tideglusib | CAS 865854-05-3

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