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UF-010 Catalog No : 16122842

Chemical Information

Product NameUF-010
Iupac Chemical NameUF-010 
SynonymsUF-010; UF 010; UF010 
Molecular FormulaC11H15BrN2O 
Molecular Weight271.158 
InChiKey
InChi
Cas537672-41-6

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

UF-010 is a Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 M for HDACs 3, 2, 1 and 8, respectively). UF010 inhibits cancer cell proliferation via class I HDAC inhibition. This causes global changes in protein acetylation and gene expression, resulting in activation of tumor suppressor pathways and concurrent inhibition of several oncogenic pathways. The isotype selectivity coupled with interesting biological activities in suppressing tumor cell proliferation support further preclinical development of the UF010 class of compounds for potential therapeutic applications. 

Chemical Structure

16122842 - UF-010 | CAS 537672-41-6

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