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VX-702 Catalog No : 16070804

Chemical Information

Product NameVX-702
Iupac Chemical Name6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide 
SynonymsVX702; VX 702 
Molecular FormulaC19H12F4N4O2 
Molecular Weight404.31779 
SmileNC(=O)N(C1=CC=C(C(=N1)C1=C(C=C(C=C1)F)F)C(=O)N)C1=C(C=CC=C1F)F
InChiKeyFYSRKRZDBHOFAY-UHFFFAOYSA-N
InChiInChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)
Cas745833-23-2

Technical Data

AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

VX-702, one of a series of second-generation, is an orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases. VX-702 prevents activation of p38MAPK and decrements in many platelet storage parameters after exposure to 16 C without agitation for 24 h.  

Chemical Structure

16070804 - VX-702 | CAS 745833-23-2

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