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Vadadustat(AKB-6548) Catalog No : 6121401

Chemical Information

Product NameVadadustat(AKB-6548)
Iupac Chemical Name(5-(3-chlorophenyl)-3-hydroxypicolinoyl)glycine 
SynonymsVadadustat;AKB-6548 
Molecular FormulaC14H11ClN2O4 
Molecular Weight306.7 
SmileO=C(O)CNC(C1=NC=C(C2=CC=CC(Cl)=C2)C=C1O)=O
InChiKeyJGRXMPYUTJLTKT-UHFFFAOYSA-N
InChiInChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)
Cas1000025-07-9

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO, not in water 
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years) 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

Vadadustat (AKB-6548), a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase inhibitor induces endogenous erythropoietin synthesis and enhances iron mobilization.

 

Chemical Structure

6121401 - Vadadustat(AKB-6548) | CAS 1000025-07-9

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