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Varlitinib Catalog No : 2017885

Chemical Information

Product NameVarlitinib
Iupac Chemical Name(R)-N4-(3-Chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazolin 
SynonymsAR-00334543;ARRY-334543;Varlitinib Ditosylate;ARRY 334543 (Varlitinib) 
Molecular FormulaC22H19ClN6O2S 
Molecular Weight466.94326 
SmileCC1COC(=N1)Nc2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5nccs5
InChiKeyUWXSAYUXVSFDBQ-UHFFFAOYSA-N
InChiInChI=1S/C22H19ClN6O2S/c1-13-10-31-22(27-13)29-14-2-4-18-16(8-14)21(26-12-25-18)28-15-3-5-19(17(23)9-15)30-11-20-24-6-7-32-20/h2-9,12-13H,10-11H2,1H3,(H,27,29)(H,25,26,28)
Cas845272-21-1
MDLMFCD18251455

Technical Data

Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

ARRY334543 is a potent selective ErbB-1 and ErbB-2 inhibitor (IC50=7and 2 nM, respectively).  

Chemical Structure

2017885 - Varlitinib | CAS 845272-21-1

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