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Vatalanib Catalog No : 010434

Chemical Information

Product NameVatalanib
Iupac Chemical NameN-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine 
SynonymsPTK787; PTK/ZK; CGP-79787; ZK-222584 
Molecular FormulaC20H15ClN4 
Molecular Weight346.813 
SmileC1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4
InChiKeyYCOYDOIWSSHVCK-UHFFFAOYSA-N
InChiInChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
Cas212141-54-3

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Vatalanib free base is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. 

Chemical Structure

010434 - Vatalanib | CAS 212141-54-3

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