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WIKI4 Catalog No : 73102

Chemical Information

Product NameWIKI4
Iupac Chemical Name2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione 
SynonymsWIKI-4 
Molecular FormulaC29H23N5O3S 
Molecular Weight521.59 
SmileCOC1=CC=C(C=C1)N1C(=NN=C1C1=CC=NC=C1)SCCCN1C(C2=CC=CC=3C2=C(C1=O)C=CC3)=O
InChiKeyRNUXIZKXJOGYQP-UHFFFAOYSA-N
InChiInChI=1S/C29H23N5O3S/c1-37-22-11-9-21(10-12-22)34-26(20-13-15-30-16-14-20)31-32-29(34)38-18-4-17-33-27(35)23-7-2-5-19-6-3-8-24(25(19)23)28(33)36/h2-3,5-16H,4,17-18H2,1H3
Cas838818-26-1

Technical Data

AppearanceOff-white solid powder 
Purity97% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

WIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2, and leads to inhibition of Wnt/beta-catenin signaling. 

Chemical Structure

73102 - WIKI4 | CAS 838818-26-1

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