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XL765 Catalog No : 111910

Chemical Information

Product NameXL765
Iupac Chemical NameN-[4-[[3-(3,5-dimethoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-3-methoxy-4-methylbenzamide 
Synonymscc-497 
Molecular FormulaC31H29N5O6S 
Molecular Weight599.657 
SmileCC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
InChiKeyHJSSPYJVWLTYHG-UHFFFAOYSA-N
InChiInChI=1S/C31H29N5O6S/c1-19-9-10-20(15-28(19)42-4)31(37)33-21-11-13-25(14-12-21)43(38,39)36-30-29(34-26-7-5-6-8-27(26)35-30)32-22-16-23(40-2)18-24(17-22)41-3/h5-18H,1-4H3,(H,32,34)(H,33,37)(H,35,36)
Cas1123889-87-1

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

XL765 is a PI3K/mTOR dual kinase inhibitor with IC50 values of 157 nM, 39 nM, 113 nM, 9 nM and 43 nM for mTOR, p110, p110, p110 and p110, respectively. 

Chemical Structure

111910 - XL765 | CAS 1123889-87-1

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