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XMD16-5 Catalog No : 17021312

Chemical Information

Product NameXMD16-5
Iupac Chemical NameXMD16-5 
SynonymsN/A 
Molecular FormulaC23H24N6O2 
Molecular Weight416.48 
InChiKey
InChi
Cas1345098-78-3

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.

XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.

 

Chemical Structure

17021312 - XMD16-5 | CAS 1345098-78-3

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