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XMD8-87 Catalog No : 17021311

Chemical Information

Product NameXMD8-87
Iupac Chemical NameXMD8-87 
SynonymsN/A 
Molecular FormulaC24H27N7O2 
Molecular Weight445.52 
InChiKey
InChi
Cas1234480-46-6

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations.

XMD8-87 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.

 

Chemical Structure

17021311 - XMD8-87 | CAS 1234480-46-6

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