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Y-27632 dihydrochloride Catalog No : 010421

Chemical Information

Product NameY-27632 dihydrochloride
Iupac Chemical Name4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride 
SynonymsY 27632 dihydrochloride; Y27632 dihydrochloride 
Molecular FormulaC14H23Cl2N3O 
Molecular Weight320.258 
SmileC[[email protected]](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
InChiKeyIDDDVXIUIXWAGJ-DDSAHXNVSA-N
InChiInChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1
Cas129830-38-2

Technical Data

AppearanceSolid powder 
Purity97% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. 

Chemical Structure

010421 - Y-27632 dihydrochloride | CAS 129830-38-2

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