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YF-2 hydrochloride Catalog No : 193151

Chemical Information

Product NameYF-2 hydrochloride
SynonymsYF-2 hydrochloride;YF-2 HCI.
Molecular FormulaC20H23Cl2F3N2O3
Molecular Weight467.31
SmileO=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C.Cl
InChiKey
InChi
Cas1312005-62-1

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activitor, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease.

Chemical Structure

193151 - YF-2 hydrochloride  | CAS 1312005-62-1

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