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ZK-756326 dihydrochloride Catalog No : 16122850

Chemical Information

Product NameZK-756326 dihydrochloride
Iupac Chemical NameZK-756326 dihydrochloride 
SynonymsZK-756326; ZK 756326; ZK756326; ZK-756326 dihydrochloride 
Molecular FormulaC21H30Cl2N2O3 
Molecular Weight429.382 
InChiKey
InChi
Cas1780259-94-0

Technical Data

Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM. ZK 756326 was a full agonist of CCR8, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1. 

Chemical Structure

16122850 - ZK-756326 dihydrochloride | CAS 1780259-94-0

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