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ZM 323881 hydrochloride Catalog No : 122214

Chemical Information

Product NameZM 323881 hydrochloride
Iupac Chemical Name5-((7-Benzyloxyquinazolin-4-yl)amino)-4-fluoro-2-methylphenol hydrochloride
SynonymsZM 323881; ZM-323881
Molecular FormulaC22H19ClFN3O2
Molecular Weight411.857
SmileCl.C(C1=CC=CC=C1)OC1=CC=C2C(=NC=NC2=C1)NC=1C(=CC(=C(C1)O)C)F
InChiKeyAVRHWGLIYGJSOD-UHFFFAOYSA-N
InChiInChI=1S/C22H18FN3O2.ClH/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15;/h2-11,13,27H,12H2,1H3,(H,24,25,26);1H
Cas324077-30-7

Technical Data

AppearanceSolid powder
Purity98%
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
Quality control

Description

 ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM).

Chemical Structure

122214 - ZM 323881 hydrochloride | CAS 324077-30-7

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