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AT7867 编号 : 161009021

化学信息

产品英文名称AT7867
Iupac 化学名称4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine 
同义词AT7867; AT 7867; AT-7867; AT7867 HCl; AT7867 dihydrochloride. AT7867 hydrochloride. 
英文同义词AT7867; AT 7867; AT-7867; AT7867 HCl; AT7867 dihydrochloride. AT7867 hydrochloride. 
分子式C20H20ClN3 
分子量337.8459 
SmileN1N=CC(=C1)C1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)Cl
InChiKeyLZMOSYUFVYJEPY-UHFFFAOYSA-N
InChiInChI=1S/C20H20ClN3/c21-19-7-5-18(6-8-19)20(9-11-22-12-10-20)17-3-1-15(2-4-17)16-13-23-24-14-16/h1-8,13-14,22H,9-12H2,(H,23,24)
Cas857531-00-1 (free base); 1431697-86-7 (2HCl)

技术数据

外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
质量控制

产品详情

This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at the cellular level, as measured by inhibition of GSK3beta and S6 ribosomal protein phosphorylation, and also causes growth inhibition in a range of human cancer cell lines as a single agent. 

结构

161009021 - AT7867 | CAS 857531-00-1 (free base); 1431697-86-7 (2HCl)

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